The enzyme reaction rate activity allows students to simulate the effects of variables such as temperature and pH on the reaction rate of the enzyme catalase. This computer simulation is best used after the students have done a wet lab experiment. The value of the simulation is that it requires the students to interpret and analyze the graphical representation of data and it enables the running of mutiple experiments in a short amount of time.

TEACHER RESOURCES Teacher Materials Student Activity Student    Assessment Learning    Goals/Standards COMPUTER MODEL Based on a model from Rick Heupel, Tucson, AZ PC Format Mac Format STELLATM software Web-based Simulation AUTHORS Don Shaffer   North East HS   North East, MD George Morse   Winston Churchill HS   Potomac, MD Kevin Wallace   Allegany HS   Cumberland, MD Aline Novak   Clear Springs HS   Clear Springs, MD Janet Hartlove   Western HS   Baltimore, MD

THE MODEL DIAGRAM THE EQUATIONS Hydrogen_Peroxide(t) = Hydrogen_Peroxide(t - dt) + (-H2O2_Catalysis_Rate) * dt INIT Hydrogen_Peroxide = 1*10^(Hydrogen_Peroxide_Exponent) H2O2_Catalysis_Rate(i) = H2O2_Catalysis_Rate(o) * CONVERSION MULTIPLIER CONVERSION MULTIPLIER = 0.5 Oxygen(t) = Oxygen(t - dt) + (H2O2_Catalysis_Rate) * dt INIT Oxygen = 0 H2O2_Catalysis_Rate(i) = H2O2_Catalysis_Rate(o) * CONVERSION MULTIPLIER CONVERSION MULTIPLIER = 0.5 Water(t) = Water(t - dt) + (H2O2_to_Water_Rate) * dt INIT Water = 0 H2O2_to_Water_Rate = H2O2_Catalysis_Rate Available_Enzyme = 5 Enzyme_Rate = 6e6 * pH_Effect*Temperature_Effect Hydrogen_Peroxide_Exponent = 8 pH = 7.0 Temperature = 20 pH_Effect = GRAPH(pH) (0.00, 0.00), (1.08, 0.00), (2.15, 0.00), (3.23, 0.00), (4.31, 0.2), (5.38, 0.8), (6.46, 1.00), (7.54, 1.00), (8.62, 0.8), (9.69, 0.2), (10.8, 0.00), (11.8, 0.00), (12.9, 0.00), (14.0, 0.00) Temperature_Effect = GRAPH(Temperature) (0.00, 0.01), (7.14, 0.1), (14.3, 0.5), (21.4, 1.00), (28.6, 1.00), (35.7, 1.00), (42.9, 0.9), (50.0, 0.5), (57.1, 0.005), (64.3, 0.00), (71.4, 0.00), (78.6, 0.00), (85.7, 0.00), (92.9, 0.00), (100.0, 0.00)

THE OUTPUT

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